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Edgardo D Carosella Selected Research

HLA-G Antigens (HLA G)

5/2022The HLA-G immune checkpoint: a new immuno-stimulatory role for the α1-domain-deleted isoform.
11/2021HLA-G gene editing in tumor cell lines as a novel alternative in cancer immunotherapy.
10/2021Tumor infiltrating and peripheral CD4+ILT2+ T cells are a cytotoxic subset selectively inhibited by HLA-G in clear cell renal cell carcinoma patients.
5/2021Role of the HLA-G immune checkpoint molecule in pregnancy.
1/2021HLA-G/LILRBs: A Cancer Immunotherapy Challenge.
7/2020The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma.
1/2020Soluble HLA-G and HLA-G Bearing Extracellular Vesicles Affect ILT-2 Positive and ILT-2 Negative CD8 T Cells Complementary.
11/2019Influence of hormones on the immunotolerogenic molecule HLA-G: a cross-sectional study in patients with congenital adrenal hyperplasia.
10/2019The Autoimmune Regulator (Aire) transactivates HLA-G gene expression in thymic epithelial cells.
10/2019CD8+PD-1-ILT2+ T Cells Are an Intratumoral Cytotoxic Population Selectively Inhibited by the Immune-Checkpoint HLA-G.
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Edgardo D Carosella Research Topics

Disease

56Neoplasms (Cancer)
05/2022 - 07/2002
14Melanoma (Melanoma, Malignant)
01/2018 - 07/2002
7Renal Cell Carcinoma (Grawitz Tumor)
11/2021 - 01/2004
6Choriocarcinoma
11/2021 - 11/2003
6Hypoxia (Hypoxemia)
10/2016 - 04/2007
6Infections
12/2009 - 02/2002
5Virus Diseases (Viral Diseases)
10/2015 - 01/2003
4Glioblastoma (Glioblastoma Multiforme)
01/2017 - 01/2004
3Neoplasm Metastasis (Metastasis)
07/2020 - 08/2015
3Autoimmune Diseases (Autoimmune Disease)
02/2014 - 11/2008
3Papillomavirus Infections
03/2012 - 11/2008
3Carcinoma (Carcinomatosis)
12/2009 - 08/2003
2Genetic Predisposition to Disease (Genetic Predisposition)
01/2017 - 02/2005
2Glioma (Gliomas)
09/2016 - 02/2013
2Hematologic Neoplasms (Hematological Malignancy)
01/2014 - 05/2008
2Pregnancy Complications
05/2012 - 09/2009
2Leukemia
12/2009 - 05/2005
2Uterine Cervical Neoplasms (Cancer of the Cervix)
08/2009 - 11/2008
2Breast Neoplasms (Breast Cancer)
10/2003 - 03/2002
2Inflammation (Inflammations)
02/2003 - 03/2002
1Vascular Remodeling
05/2021
1Respiratory Insufficiency (Respiratory Failure)
01/2021
1COVID-19
01/2021
1Wounds and Injuries (Trauma)
01/2021
1Carcinogenesis
07/2020
1Cardiovascular Diseases (Cardiovascular Disease)
01/2020
1Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
11/2019
1Non-Muscle Invasive Bladder Neoplasms
09/2018
1Macular Degeneration (Age-Related Maculopathy)
07/2018
1Hodgkin Disease (Hodgkin's Disease)
12/2017
1Urologic Neoplasms (Urological Cancer)
08/2015
1Urinary Bladder Neoplasms (Bladder Cancer)
08/2015
1Kidney Neoplasms (Kidney Cancer)
08/2015
1Prostatic Neoplasms (Prostate Cancer)
08/2015
1Acute Erythroblastic Leukemia (Erythroleukemia)
02/2014
1Ascites
06/2012
1Mouth Neoplasms (Oral Cancer)
03/2012
1Ovarian Neoplasms (Ovarian Cancer)
12/2009
1Squamous Intraepithelial Lesions
08/2009
1Telangiectasis (Telangiectasia)
06/2009
1Arthralgia (Joint Pain)
06/2009
1Systemic Scleroderma (Systemic Sclerosis)
06/2009
1Ulcer
06/2009
1Hematologic Diseases (Blood Diseases)
11/2008
1Pre-Eclampsia (Preeclampsia)
09/2008
1Spontaneous Abortion (Miscarriage)
09/2008
1Graft vs Host Disease (Graft-Versus-Host Disease)
01/2008
1Septic Shock (Toxic Shock Syndrome)
08/2007

Drug/Important Bio-Agent (IBA)

69HLA-G Antigens (HLA G)IBA
05/2022 - 02/2002
12HLA Antigens (Human Leukocyte Antigens)IBA
01/2020 - 11/2005
8Proteins (Proteins, Gene)FDA Link
09/2016 - 11/2003
5Protein Isoforms (Isoforms)IBA
05/2022 - 11/2003
4AntibodiesIBA
11/2021 - 03/2002
4Complementary DNA (cDNA)IBA
10/2019 - 07/2002
4Messenger RNA (mRNA)IBA
09/2016 - 10/2005
3Biomarkers (Surrogate Marker)IBA
01/2021 - 11/2019
3Immune Checkpoint ProteinsIBA
01/2020 - 08/2015
3Histocompatibility Antigens Class IIBA
12/2009 - 01/2004
2LigandsIBA
07/2020 - 07/2002
2CalciumIBA
05/2020 - 03/2012
2Immune Checkpoint InhibitorsIBA
10/2019 - 08/2015
2LuciferasesIBA
01/2018 - 09/2016
2Neoplasm Antigens (Tumor Antigens)IBA
11/2014 - 11/2003
2InterferonsIBA
02/2013 - 06/2012
2HLA-A Antigens (HLA-A)IBA
11/2008 - 07/2002
2ParaffinIBA
01/2004 - 03/2002
1E-SelectinIBA
01/2021
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2020
1CD40 Ligand (CD40L)IBA
07/2020
1Steroid 21-Hydroxylase (21 Hydroxylase)IBA
11/2019
1EnzymesIBA
11/2019
1Hormones (Hormone)IBA
11/2019
1Hydrocortisone (Cortisol)FDA LinkGeneric
11/2019
1ProgesteroneFDA LinkGeneric
11/2019
1AndrogensIBA
11/2019
13' Untranslated Regions (3' UTR)IBA
01/2017
1A-Form DNA (A-DNA)IBA
09/2016
1ElementsIBA
09/2016
1Cytotoxins (Cytolysins)IBA
05/2016
1Pharmaceutical PreparationsIBA
08/2015
1IpilimumabIBA
08/2015
1Blocking AntibodiesIBA
08/2015
1Immunoglobulins (Immunoglobulin)IBA
11/2014
1DecitabineFDA Link
02/2013
1LipidsIBA
03/2012
1Cyclin-Dependent Kinase Inhibitor p16IBA
11/2008
1DNA (Deoxyribonucleic Acid)IBA
09/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2007
1Monoclonal AntibodiesIBA
09/2007
1Amino AcidsFDA Link
09/2007
1Membrane Proteins (Integral Membrane Proteins)IBA
08/2007

Therapy/Procedure

10Immunotherapy
11/2021 - 10/2011
9Therapeutics
01/2021 - 03/2005
5Transplantation
02/2011 - 07/2007
3Organ Transplantation
04/2007 - 01/2003
2Drug Therapy (Chemotherapy)
05/2016 - 10/2003
2Radiotherapy
05/2016 - 02/2005
1Cystectomy
08/2015
1Cell- and Tissue-Based Therapy (Cell Therapy)
02/2011
1Cell Transplantation
01/2008